As resident microglia decline, they appear to be replaced by cells with stronger inflammatory signals and blood-derived immune traits.
As resident microglia decline, they appear to be replaced by cells with stronger inflammatory signals and blood-derived immune traits.
More from this article
See all →The apparent replacement of resident microglia challenges the assumption that these embryonically…
Why resident microglia disappear with age, and whether their replacement drives Alzheimer’s or…
From roughly age 50 to 75, the hippocampus gradually loses microglia, its main immune cells.
Aging is linked to fewer cells maintaining the blood-brain barrier, potentially weakening the…
Immune remodeling in the hippocampus appears to begin during midlife, potentially connecting aging…
Gene-expression data alone misses immune-cell identity and lineage changes revealed by 3D genome…
Researchers used single-cell analyses of postmortem hippocampal tissue from 40 neurologically…
Don't lose this one
A free account saves cards like this to your Collection, and Korva resurfaces them so you actually remember.