Investor Says a Snake Collector Who Injected Himself With Venom Helped Save Thousands
The account is secondhand and thin, but the investor said the collector moved venom science forward.

This Week in Startups · Why this longevity startup raised in Japan, not Silicon Valley | TWiST Tokyo | E2315Jason Calacanis, a startup investor speaking on a podcast recorded in Tokyo, reached for an extreme case to make his point about medical risk. There was a guy, he said, who collected venomous snakes.
The man "injected himself with the snake venom to build up a tolerance for it," Calacanis said, doing it on his own "so he could handle his own snakes."
Calacanis raised the account during a podcast interview about the right to try and risky volunteer trials. He described people willing during COVID to be infected and then given a possible treatment to help the world.
That choice seemed admirable to him, Calacanis said. He called it "a beautiful thing for somebody to do," and he compared such volunteers to astronauts, soldiers, and firefighters who accept danger for society.
Bilal, a guest from Eeki Labs working on aging research, said deliberately making someone sick crossed a line for him. He said "we do not burn the skin of firefighters to then study" how skin heals.
Calacanis then offered the snake collector as a different arrangement, in his telling a person experimenting on himself rather than researchers sickening a volunteer. He named no source or study for the account. According to Calacanis's secondhand version, the man's blood plasma was able to help create the antidotes for toxins, and he moved that science forward.
Calacanis said he did not know what to call those antidotes for poisons and toxins like this. He put the effect in personal terms, saying, "He saved thousands of lives, I believe," and said his team would post a link with more detail.
What he gave the audience left much unresolved. There was no account of how many injections were involved, how sick the man became, or which researchers used his plasma.
Questions people ask
What is antivenom and how is it normally made?
Antivenom is a medicine that neutralizes snake venom after a bite. It is usually made by giving small, safe amounts of venom to an animal such as a horse, then collecting the antibodies its immune system produces and purifying them for human use.
Can small doses of venom build tolerance?
The immune system can respond more strongly after repeated, controlled exposure, which is the principle behind some allergy treatments and animal immunization. With venom, any such protection is partial and unpredictable, because venoms contain complex toxins that can damage nerves, blood, tissue, and organs.
Is it safe to try injecting venom yourself?
No. Self injection can cause severe allergic reaction, organ damage, infection, and death, and there is no safe home dose. Research immunization is done under medical supervision with purified materials, emergency care, and laboratory testing.