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One Bad Night of Sleep Leaves You 25 Percent More Resistant to Insulin the Next Day

It also raises cortisol and lowers leptin, the fullness signal, so cravings rise just when the body handles food worse.

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The Metabolism and Menopause Podcast · 10 Secrets From Women Who Lost 30+ Pounds And Kept It Off | MMP Ep. 332

Stephanie Crassweller, who coaches women in midlife on weight loss, says one night of poor sleep leaves you 25 percent more resistant to insulin the next day.

Crassweller says her clients called sleep one of the most underrated tools they used. Insulin resistance means the body needs more insulin to manage blood sugar, so blood sugar stays higher longer after eating.

The same short night also raises cortisol, the stress hormone, and inflammation, she says. At the same time, it lowers leptin, the hormone that tells the brain you are full and signals the body to burn fat.

So cravings get worse. Crassweller notes that in perimenopause and postmenopause, declining hormones already tilt the body toward losing muscle, which is why she urges progressive resistance training.

Questions people ask

What does being more insulin resistant actually feel like?

It means your cells respond less well to insulin, so blood sugar stays higher longer after you eat. You may feel hungrier, more tired, and more prone to cravings, especially for carbs and sweets. Over time, repeated insulin resistance raises the risk for type 2 diabetes.

What is leptin and what does it do?

Leptin is a hormone made mainly by fat tissue that tells the brain you have enough energy stored and can stop eating. When leptin drops after poor sleep, hunger rises and satiety feels weaker. It also helps regulate energy use, which is why researchers link it to fat burning.

How much sleep is enough to avoid this effect?

Most adults do best with seven to nine hours, with consistent bedtimes and wake times. Dark, cool, and quiet rooms, plus less caffeine and alcohol late in the day, help most people fall and stay asleep. If you snore loudly, gasp, or feel exhausted despite enough time in bed, talk to a doctor.